The inactivation of human aldehyde oxidase 1 by hydrogen peroxide and superoxide

Hydrogen Peroxide Inhibition and Inactivation of Bicupin Oxalate Oxidase

................................................................................................................ iii TABLE OF CONTENTS .............................................................................................. iv LIST OF ABBREVIATIONS ........................................................................................ x CHAPTER 1: INTRODUCTION ..............................

Reversible inactivation by hydrogen peroxide

Great Britain Reduction and Inactivation of Superoxide Dismutase by Hydrogen Peroxide By ROBERT C . BRAY

By ROBERT C. BRAY and STEPHEN A. COCKLE School ofMolecular Sciences, University ofSussex, Falmer, Brighton BN1 9QJ, Sussex, U.K. and E. MARTIN FIELDEN and PETER B. ROBERTS Division ofPhysics, Institute of Cancer Research, Clifton Avenue, Sutton, Surrey, U.K. and GIUSEPPE ROTILIO and LILIA CALABRESE Centro di Biological Molecolare del C.N. R., Istituto di Chimica Biologica, Universita di Roma, R...

Superoxide, Hydrogen Peroxide, and Singlet Oxygen in Lipid Peroxidation by a Xanthine Oxidase System*

1. Xanthine oxidase acting aerobically upon acetaldehyde was found to cause the peroxidation of linolenate. This was demonstrated by increased absorbance at 233 nm due to diene conjugation and by the detection of a lipid peroxide spot on thin layer chromatograms. 2. Superoxide dismutase inhibited this lipid peroxidation, as did catalase, thus indicating that both O,m and H,O, were essential int...

Superoxide, hydrogen peroxide, and singlet oxygen in lipid peroxidation by a xanthine oxidase system.

1. Xanthine oxidase acting aerobically upon acetaldehyde was found to cause the peroxidation of linolenate. This was demonstrated by increased absorbance at 233 nm due to diene conjugation and by the detection of a lipid peroxide spot on the thin layer chromatograms. 2. Superoxide dismutase inhibited this lipid peroxidation, as did catalase, thus indicating that both O2- and H2O2 were essential...